About acowan

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So far acowan has created 19 blog entries.

New publication of novel free-boundary model of a moving cell

December 7th, 2017|News, NRCAM publication|

11-14-2017. A new publication, Nickaeen et al. 2017, from the VCell team describes a novel free-boundary model of actin -myosin contractility that couples force-balance and myosin transport equations. A previously developed mass-conservation algorithm originally developed for VCell to solve parabolic equations in moving domains with know kinematics was augmented by coupling with the FronTier front-tracking software and a segregated solver.

SpringSaLaD version 2 released

December 7th, 2017|News, NRCAM publication, Uncategorized|

11-30-2017. Version 2 of the SpringSaLaD software was released today. The primary new feature is the ability to directly build models from atomic coordinates in pdb files, using an interactive 3D viewer to compare the course-grained linked spheres representation in SpringSaLaD with the PDB structure.

biomodel-116929971

August 30th, 2017|Uncategorized|

Name: “Dreyer_2017_AIMS Biophysics”
Saved: Tue, 31 May 2016  13:42:11 GMT
vcell identifier: biomodel-116929912
Owned by: “idreyer”

download model (.vcml)

biomodel-116929912

August 30th, 2017|Uncategorized|

Name: “Dreyer_2017_AIMS Biophysics”
Saved: Tue, 31 May 2016  13:42:11 GMT
vcell identifier: biomodel-116929912
Owned by: “idreyer”

download model (.vcml)

biomodel-116930032

August 30th, 2017|Uncategorized|

Name: “Wittek_et_al_JIntegrPlantBiol_2017_Phloem Fungus”
Saved: Tue, 31 May 2016  13:42:11 GMT
vcell identifier: biomodel-116930032
Owned by: “idreyer”

download model (.vcml)

Acevedo et. al 2017

August 24th, 2017|publication, publication-2017|

A Noncanonical Binding Site in the EVH1 Domain of VASP Regulates Its Interactions with the Proline Rich Region of Zyxin
Acevedo, LA, Greenwood, AI, Nicholson, LK
Biochemistry. Aug 23.
PMID: 28783324    doi:10.1021/acs.biochem.7b00618

New published model of the PLC/PKC pathway

July 10th, 2017|News, NRCAM publication, Uncategorized, VCell Posts|

2017-07-10. A new publication in Biophysical Journal by Mohan et al. uses a VCell model to define mechanisms for signal amplification in the PLC/PKC pathway during chemotaxis.  Link to the publication and view model details from our Published Models listing.

Summer Research Projects

July 1st, 2017|CCAM Events, News, Uncategorized, VCell Posts|

7-1-2017.  CCAM welcomes several undergraduates and a graduate rotation student who are working on projects related to VCell this summer . Undergraduate students include Keeyan Ghoreshi, Anvin Thomas, Natalie de la Garrique and Shahan Kamal from UConn Storrs and Kevin Gaffney from the University of Oklahoma. Joe Masison is a new MD/PhD student from University of Maryland. Keeyan is working on the infrastructure for Sloppy Modeling projects, Shahan is modeling pathways using high-throuput data, Natalie […]

VCell model of Plant and fungal transporters

May 10th, 2017|News, NRCAM publication|

2017-05-10. A VCell model has recently been published by Wittek et al. that describes the battle between fungal and plant  sugar transporters. View model details from our Published Models listing.

New VCell model of kidney podocyte cytoskeleton

March 10th, 2017|News, NRCAM publication|

2017-03-10. A new model from the Iyengar and Loew laboratories examines how cytoskeletal dynamics effect local changes in the complex morphology of kidney podocytes. Link to the publication and view model details from our Published Models listing.