About acowan

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So far acowan has created 26 blog entries.

VCell 7.0 with kinematics released to beta

2018-03-16T19:12:53+00:00 March 15th, 2018|News, VCell Posts|

VCell 7.0 has been released to the public beta site.  VCell 7 includes new 2D kinematics functionality for solving reaction diffusion equations within moving boundaries.  To support models of cell motility and morphogenesis, this allows users to specify velocities of points, surfaces and volumes within the geometry.  Other features in VCell 7.0 are methods for creating simulated fluorescence for direct comparison to microscopy data, the ability to use COMSOL Multiphysics solver (requires a local COMSOL license) and adaptive […]

Leslie Loew awarded 2018 Biophysical Society Distinguished Service Award

2018-03-16T15:02:48+00:00 February 21st, 2018|News|

2018-02-21.  Leslie Loew received the Distinguished Service Award of the Biophysical Society at its 2017 annual meeting February 17-21. The award acknowledged his ongoing commitment to the Society and his dedicated service as Editor-in-Chief of Biophysical Journal. Congratulations to Les for this well-deserved award.

SpringSaLaD version 2 released

2017-12-07T18:45:57+00:00 December 7th, 2017|News, NRCAM publication|

11-30-2017. Version 2 of the SpringSaLaD software was released today. The primary new feature is the ability to directly build models from atomic coordinates in pdb files, using an interactive 3D viewer to compare the course-grained linked spheres representation in SpringSaLaD with the PDB structure.

New publication of novel free-boundary model of a moving cell

2018-03-16T19:28:29+00:00 December 7th, 2017|News, NRCAM publication|

11-14-2017. A new publication, Nickaeen et al. 2017, from the VCell team describes a novel free-boundary model of actin -myosin contractility that couples force-balance and myosin transport equations. A previously developed mass-conservation algorithm originally developed for VCell to solve parabolic equations in moving domains with know kinematics was augmented by coupling with the FronTier front-tracking software and a segregated solver.

New model of SH2 binding to EGFR published

2018-02-20T19:35:24+00:00 November 25th, 2017|News, NRCAM publication|

2017-11-25.  A new VCell model explores the effect of SH2 domain overexpression on the EGFR signaling pathway in a publication by Jadwin et al.   The results suggest that signaling via SH2 domain binding is buffered over a wide range of concentrations. Explore the model from the listing on our Published Models page