Name: “Smith et al 2002 Systems Analysis of Ran Transport”
Saved: Tue, 11 Oct 2005  16:56:55 GMT
vcell identifier: biomodel-14272976
Owned by: “les”

download model (.vcml)

Compartments, Species, Reactions
  • Compartment "Cytosol".   (type: Volume)
    • Species "Carrier_Cytosol"
    • Species "Carrier_RanGTP_Cytosol"
    • Species "RanGAP_Cytosol"
    • Species "RanBP1_Cytosol"
    • Species "RanBP1_Carrier_RanGTP_Cytosol"
    • Species "RanGDP_Cytosol"
    • Species "NTF2_RanGDP_Cytosol"
    • Species "FRanGTP_Cytosol"
    • Species "FCarrier_RanGTP_Cytosol"
    • Species "FRanGDP_Cytosol"
    • Species "FNTF2_RanGDP_Cytosol"
    • Species "FRanBP1_Carrier_RanGTP_Cytosol"
    • Species "NTF2_Cytosol"
    • Species "Pipet_Cytosol"
    • Species "RanGTP_Cytosol"
    • Reaction "Carrier FRanGTP binding"   (Carrier_Cytosol + FRanGTP_Cytosol → FCarrier_RanGTP_Cytosol)
    • Reaction "FRanGTP dephosphorylation"   (FRanGTP_Cytosol → FRanGDP_Cytosol)
    • Reaction "dephosphorylationF"   (FRanBP1_Carrier_RanGTP_Cytosol → FRanGDP_Cytosol + RanBP1_Cytosol + Carrier_Cytosol)
    • Reaction "NTF2_FRanGDP Unbinding"   (NTF2_Cytosol + FRanGDP_Cytosol → FNTF2_RanGDP_Cytosol)
    • Reaction "RanBP1 bindingF"   (FCarrier_RanGTP_Cytosol + RanBP1_Cytosol → FRanBP1_Carrier_RanGTP_Cytosol)
    • Reaction "Microinj"   (∅ → FRanGDP_Cytosol)
    • Reaction "RanGTP dephosphorylation"   (RanGTP_Cytosol → RanGDP_Cytosol)
    • Reaction "NTF2_RanGDP Unbinding"   (RanGDP_Cytosol + NTF2_Cytosol → NTF2_RanGDP_Cytosol)
    • Reaction "dephosphorylation"   (RanBP1_Carrier_RanGTP_Cytosol → RanGDP_Cytosol + Carrier_Cytosol + RanBP1_Cytosol)
    • Reaction "Carrier RanGTP binding"   (RanGTP_Cytosol + Carrier_Cytosol → Carrier_RanGTP_Cytosol)
    • Reaction "RanBP1 binding"   (RanBP1_Cytosol + Carrier_RanGTP_Cytosol → RanBP1_Carrier_RanGTP_Cytosol)
  • Compartment "EC".   (type: Volume)
  • Compartment "Nucleus".   (type: Volume)
    • Species "NTF2_Nucleus"
    • Species "RanGDP_Nucleus"
    • Species "RCC1_Nucleus"
    • Species "RanGTP_Nucleus"
    • Species "NTF2_RanGDP_Nucleus"
    • Species "Carrier_Nucleus"
    • Species "Carrier_RanGTP_Nucleus"
    • Species "FCarrier_RanGTP_Nucleus"
    • Species "FRanGDP_Nucleus"
    • Species "FNTF2_RanGDP_Nucleus"
    • Species "FRanGTP_Nucleus"
    • Reaction "FRanGTP Carrier binding"   (Carrier_Nucleus + FRanGTP_Nucleus → FCarrier_RanGTP_Nucleus)
    • Reaction "NTF2_FRanGDP unbinding"   (FNTF2_RanGDP_Nucleus → NTF2_Nucleus + FRanGDP_Nucleus)
    • Reaction "FRanGDP to FRanGTP"   (FRanGDP_Nucleus → FRanGTP_Nucleus)
    • Reaction "RanGTP Carrier binding"   (RanGTP_Nucleus + Carrier_Nucleus → Carrier_RanGTP_Nucleus)
    • Reaction "RanGDP to RanGTP"   (RanGDP_Nucleus → RanGTP_Nucleus)
    • Reaction "NTF2_RAN_Nuc_Exchange"   (4 NTF2_RanGDP_Nucleus → 4 NTF2_Nucleus + RanGDP_Nucleus + 3 RanGTP_Nucleus)
    • Reaction "NTF2_RanGDP unbinding"   (NTF2_RanGDP_Nucleus → RanGDP_Nucleus + NTF2_Nucleus)
    • Reaction "NTF2_FRAN_Nuc_Exchange"   (4 FNTF2_RanGDP_Nucleus → 4 NTF2_Nucleus + 3 FRanGTP_Nucleus + FRanGDP_Nucleus)
  • Compartment "Nuc_membrane".   (type: Membrane)
    • Reaction "Carrier_RanGTP flux"   (Carrier_RanGTP_Cytosol → Carrier_RanGTP_Nucleus)
    • Reaction "NTF2 flux"   (NTF2_Cytosol → NTF2_Nucleus)
    • Reaction "NTF2_RanGDP flux"   (NTF2_RanGDP_Cytosol → NTF2_RanGDP_Nucleus)
    • Reaction "Carrier flux"   (Carrier_Cytosol → Carrier_Nucleus)
    • Reaction "FRanGDP flux"   (FRanGDP_Cytosol → FRanGDP_Nucleus)
    • Reaction "Carrier_FRanGTP flux"   (FCarrier_RanGTP_Cytosol → FCarrier_RanGTP_Nucleus)
    • Reaction "FNTF2_RanGDP flux"   (FNTF2_RanGDP_Cytosol → FNTF2_RanGDP_Nucleus)
    • Reaction "FRanGTP flux"   (FRanGTP_Cytosol → FRanGTP_Nucleus)
    • Reaction "RanGDP flux"   (RanGDP_Cytosol → RanGDP_Nucleus)
    • Reaction "RanGTP flux"   (RanGTP_Cytosol → RanGTP_Nucleus)
  • Compartment "PM".   (type: Membrane)