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Week 1
Class topics (lecture)
- Cell Cycle: Discovering mechanisms
- Modeling: a process of investigation.
Lab (computers):
- Hands on introduction of modeling tool (Stella): cell cycle model(s).
Concept mapping cell-cycle system statements and creating rate equations in Stella.
Week2
Class time:
- Respond to lab reports from previous week.
Lab time:
- Begin group projects on modeling the group cell cycle system.
- Address the following in an initial project proposal to be turned in next period:
- What is the question to be investigated with the model?
- What data do you need from current research?
- Full instructions for the research paper to be written are provided.
Readings for Weeks 1 and 2:
- Cell Cycle chapters 1 and 2 of The Cell Cycle by Murray and Hunt, 1993
- Introduction to Modeling and Cell Cycle in A Cell Biologist's Guide to Modeling and Bioinformatics.by Holmes, 2007.
Student Presentations:
Select topic for presentation on mathematical model.
- Mathematical model topics are not the same as the cell cycle projects.
- Students select a topic from a provided list i.e. drosophila pattern formation, vesicular transport, tissue morphogenesis.
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