COPASI Optimization Methods Overview

COPASI parameter estimation provides tools to optimize parameters in non-spatial deterministic models to best fit experimental data. Parameter Estimation is run within the Virtual Cell on your own desktop rather than on our central database servers. Once you have the results of a parameter estimation, you will save the model parameters with the optimized parameter set as a newly created simulation. Thus, the results will be saved permanently as part of this Virtual Cell model.

COPASI parameter estimation has provided the following optmization solvers. Brief descriptions for different solvers are shown below. For more detailed decription, please visit COPASI website .