Name: “Mohan chemotaxis 2017”
Saved: Mon, 12 Jun 2017 19:05:00 GMT
vcell identifier: biomodel-113655498
Owned by: “jnosbis”
- Compartment "Extracellular". (type: Volume)
- Species "PDGF_gradient_extracellular"
- Species "PDGF_uniform_extracellular"
- Compartment "Nucleus". (type: Volume)
- Compartment "Cytosol". (type: Volume)
- Species "E_inactive_PLC"
- Species "C_PKC_inactive"
- Species "M_cytosolic_MARCKS"
- Species "Mp"
- Reaction "MARCKS dephosphorylation" (Mp → M_cytosolic_MARCKS)
- Compartment "plasma_membrane". (type: Membrane)
- Species "R_factor_plasmaMembrane"
- Species "RplasmaMembrane"
- Species "C1_plasmaMembrane"
- Species "C2_plasmaMembrane"
- Species "e_active_PLC"
- Species "pT_PIP2"
- Species "d_DAG"
- Species "c_DAG_PKC"
- Species "cStar"
- Species "m"
- Reaction "Rsynthesis" (∅ → RplasmaMembrane)
- Reaction "R_Turnover" (RplasmaMembrane → ∅)
- Reaction "PDGF_binding" (RplasmaMembrane → C1_plasmaMembrane)
- Reaction "C1_turnover" (C1_plasmaMembrane → ∅)
- Reaction "C1_dimerization" (2 C1_plasmaMembrane → C2_plasmaMembrane)
- Reaction "C2_uncoupling" (C2_plasmaMembrane → C1_plasmaMembrane + RplasmaMembrane)
- Reaction "C2_Internalization" (C2_plasmaMembrane → ∅)
- Reaction "PLC_receptor_binding V_PLC" (E_inactive_PLC → e_active_PLC)
- Reaction "PIP2_Synthesis" (∅ → pT_PIP2)
- Reaction "PLC catalyzed PIP2 hydrolysis" (pT_PIP2 → d_DAG)
- Reaction "PIP2_hydrolysis" (pT_PIP2 → ∅)
- Reaction "DAG_consumption" (d_DAG → ∅)
- Reaction "MARCKS phosphorylation by PKC" (m → Mp)
- Reaction "V_MARCKS" (M_cytosolic_MARCKS → m)
- Reaction "V_PKC" (d_DAG + C_PKC_inactive → cStar)
- Reaction "V_dpc" (cStar → c_DAG_PKC)
- Reaction "Vpc1" (c_DAG_PKC → cStar)
- Reaction "V_pc2" (c_DAG_PKC → cStar)
- Reaction "V_offc" (c_DAG_PKC → C_PKC_inactive + d_DAG)
- Compartment "Nuclear_Membrane". (type: Membrane)