Name: “Li2015_geometryCreatesNonlinearNuclearPKA”
Saved: Tue, 23 Dec 2014  13:46:16 GMT
vcell identifier: biomodel-93313420
Owned by: “luli”

download model (.vcml)

Compartments, Species, Reactions
  • Compartment "c0".   (type: Volume)
  • Compartment "cytosol".   (type: Volume)
    • Species "cAMPsource"
    • Species "D3497cyto"
    • Species "PP1cyto"
    • Species "PP1cyto_D34cyto"
    • Species "Dcyto"
    • Species "D97cyto_PP2Apcyto"
    • Species "R2"
    • Species "PP2Bcyto"
    • Species "PP1cyto_D3497cyto_PP2Bcyto"
    • Species "PDE10A"
    • Species "cAMP_PDE10A"
    • Species "D97cyto_PKAcyto"
    • Species "PP1cyto_D34cyto_PP2Bcyto"
    • Species "AMP"
    • Species "cAMP"
    • Species "DMNB_cAMP"
    • Species "light_spot"
    • Species "R2C"
    • Species "cAMP4_R2C2"
    • Species "cAMP4_R2C"
    • Species "cAMP3_R2C2"
    • Species "cAMP_R2C2"
    • Species "cAMP2_R2C2"
    • Species "D34cyto_PP2Bcyto"
    • Species "PKAcyto"
    • Species "D3497cyto_PP2Apcyto"
    • Species "Dcyto_PKAcyto"
    • Species "PP2Acyto_PKAcyto"
    • Species "PP2Acyto"
    • Species "cAMP4_R2"
    • Species "PP2Apcyto"
    • Species "D97cyto"
    • Species "PP1cyto_D3497cyto"
    • Species "D34cyto"
    • Species "R2C2"
    • Species "D3497cyto_PP2Bcyto"
    • Reaction "D3497cyto_PP2Bcyto_off"   (D3497cyto_PP2Bcyto → D3497cyto + PP2Bcyto)
    • Reaction "D97cyto_PKAcyto_off"   (D97cyto_PKAcyto → PKAcyto + D97cyto)
    • Reaction "D97cyto_PP2Apcyto_off"   (D97cyto_PP2Apcyto → PP2Apcyto + D97cyto)
    • Reaction "D3497cyto_PP2Apcyto_on"   (D3497cyto + PP2Apcyto → D3497cyto_PP2Apcyto)
    • Reaction "D3497cyto_PP2Bcyto_on"   (PP2Bcyto + D3497cyto → D3497cyto_PP2Bcyto)
    • Reaction "PP1cyto_D34cyto_PP2Bcyto_cat"   (PP1cyto_D34cyto_PP2Bcyto → Dcyto + PP2Bcyto + PP1cyto)
    • Reaction "PP2Acyto_PKAcyto_cat"   (PP2Acyto_PKAcyto → PKAcyto + PP2Apcyto)
    • Reaction "PP2Acyto_PKAcyto_off"   (PP2Acyto_PKAcyto → PKAcyto + PP2Acyto)
    • Reaction "photoUncaging_DMNB_cAMP"   (DMNB_cAMP → cAMP)
    • Reaction "Dcyto_PKAcyto_on"   (Dcyto + PKAcyto → Dcyto_PKAcyto)
    • Reaction "PP1cyto_D34cyto_PP2Bcyto_on"   (PP2Bcyto + PP1cyto_D34cyto → PP1cyto_D34cyto_PP2Bcyto)
    • Reaction "R2_PKAcyto_bind"   (R2 + PKAcyto → R2C)
    • Reaction "Dcyto_PKAcyto_off"   (Dcyto_PKAcyto → PKAcyto + Dcyto)
    • Reaction "D3497cyto_PP2Apcyto_cat"   (D3497cyto_PP2Apcyto → D34cyto + PP2Apcyto)
    • Reaction "PP2Acyto_PKAcyto_on"   (PP2Acyto + PKAcyto → PP2Acyto_PKAcyto)
    • Reaction "R2C_PKAcyto_bind"   (R2C + PKAcyto → R2C2)
    • Reaction "PP1cyto_D3497_off"   (PP1cyto_D3497cyto → PP1cyto + D3497cyto)
    • Reaction "D3497cyto_PP2Bcyto_cat"   (D3497cyto_PP2Bcyto → D97cyto + PP2Bcyto)
    • Reaction "Dcyto_PKAcyto_cat"   (Dcyto_PKAcyto → PKAcyto + D34cyto)
    • Reaction "PP1cyto_D34cyto_PP2Bcyto_off"   (PP1cyto_D34cyto_PP2Bcyto → PP2Bcyto + PP1cyto_D34cyto)
    • Reaction "cAMPsource2cAMP"   (cAMPsource → cAMP + cAMPsource)
    • Reaction "cAMP_PDE10A_cat"   (cAMP_PDE10A → AMP + PDE10A)
    • Reaction "PP1cyto_D34cyto_off"   (PP1cyto_D34cyto → PP1cyto + D34cyto)
    • Reaction "D34cyto_PP2Bcyto_off"   (D34cyto_PP2Bcyto → D34cyto + PP2Bcyto)
    • Reaction "D3497cyto_PP2Apcyto_off"   (D3497cyto_PP2Apcyto → PP2Apcyto + D3497cyto)
    • Reaction "D97cyto_PP2Apcyto_on"   (D97cyto + PP2Apcyto → D97cyto_PP2Apcyto)
    • Reaction "cAMP4_R2_releasecAMP"   (cAMP4_R2 → cAMP + cAMP + cAMP + R2 + cAMP)
    • Reaction "D97cyto_PP2Apcyto_cat"   (D97cyto_PP2Apcyto → Dcyto + PP2Apcyto)
    • Reaction "PP1cyto_D3497cyto_PP2Bcyto_cat"   (PP1cyto_D3497cyto_PP2Bcyto → PP1cyto + D97cyto + PP2Bcyto)
    • Reaction "cAMP_R2C2_onoff"   (cAMP + R2C2 → cAMP_R2C2)
    • Reaction "cAMP4_R2C_PKA_onoff"   (cAMP4_R2C2 → cAMP4_R2C + PKAcyto)
    • Reaction "cAMP_cAMP2_R2C2_onoff"   (cAMP + cAMP2_R2C2 → cAMP3_R2C2)
    • Reaction "cAMP4_R2_PKA_onoff"   (cAMP4_R2C → cAMP4_R2 + PKAcyto)
    • Reaction "PP1cyto_D3497cyto_on"   (D3497cyto + PP1cyto → PP1cyto_D3497cyto)
    • Reaction "PP2Apcytodephosphorylation"   (PP2Apcyto → PP2Acyto)
    • Reaction "PP1cyto_D3497cyto_PP2Bcyto_on"   (PP1cyto_D3497cyto + PP2Bcyto → PP1cyto_D3497cyto_PP2Bcyto)
    • Reaction "PP1cyto_D3497cyto_PP2Bcyto_off"   (PP1cyto_D3497cyto_PP2Bcyto → PP1cyto_D3497cyto + PP2Bcyto)
    • Reaction "cAMP_cAMP_R2C2_onoff"   (cAMP + cAMP_R2C2 → cAMP2_R2C2)
    • Reaction "D34cyto_PP2Bcyto_cat"   (D34cyto_PP2Bcyto → Dcyto + PP2Bcyto)
    • Reaction "D34cyto_PP2Bcyto_on"   (D34cyto + PP2Bcyto → D34cyto_PP2Bcyto)
    • Reaction "D97cyto_PKAcyto_on"   (D97cyto + PKAcyto → D97cyto_PKAcyto)
    • Reaction "PP1cyto_D34cyto_on"   (PP1cyto + D34cyto → PP1cyto_D34cyto)
    • Reaction "cAMP_cAMP3_R2C2_onoff"   (cAMP3_R2C2 + cAMP → cAMP4_R2C2)
    • Reaction "D97cyto_PKAcyto_cat"   (D97cyto_PKAcyto → D3497cyto + PKAcyto)
    • Reaction "cAMP_PDE10A_onoff"   (cAMP + PDE10A → cAMP_PDE10A)
  • Compartment "nucleus".   (type: Volume)
    • Species "PP2Anuc"
    • Species "Dnuc_PKAnuc"
    • Species "D97nuc_PP2Apnuc"
    • Species "PP1nuc_D34nuc_PP2Bnuc"
    • Species "D34nuc_CK2"
    • Species "Dnuc_CK2"
    • Species "PP2Anuc_PKAnuc"
    • Species "Dnuc"
    • Species "D34nuc_PP2Bnuc"
    • Species "PP1nuc"
    • Species "PP1nuc_D34nuc"
    • Species "PP1nuc_D3497nuc"
    • Species "PP1nuc_D3497nuc_PP2Bnuc"
    • Species "D3497nuc_PP2Apnuc"
    • Species "D97nuc"
    • Species "D3497nuc_PP2Bnuc"
    • Species "CK2"
    • Species "PP2Apnuc"
    • Species "PP2Bnuc"
    • Species "D34nuc"
    • Species "D3497nuc"
    • Species "PKAnuc"
    • Species "D97nuc_PKAnuc"
    • Reaction "PP1nuc_D34nuc_off"   (PP1nuc_D34nuc → PP1nuc + D34nuc)
    • Reaction "PP1nuc_D3497nuc_off"   (PP1nuc_D3497nuc → PP1nuc + D3497nuc)
    • Reaction "Dnuc_CK2_cat"   (Dnuc_CK2 → D97nuc + CK2)
    • Reaction "D97nuc_PKAnuc_cat"   (D97nuc_PKAnuc → D3497nuc + PKAnuc)
    • Reaction "PP2Anuc_PKAnuc_cat"   (PP2Anuc_PKAnuc → PP2Apnuc + PKAnuc)
    • Reaction "D97nuc_PP2Apnuc_cat"   (D97nuc_PP2Apnuc → PP2Apnuc + Dnuc)
    • Reaction "PP1nuc_D3497nuc_PP2Bnuc_cat"   (PP1nuc_D3497nuc_PP2Bnuc → PP2Bnuc + PP1nuc + D97nuc)
    • Reaction "PP1nuc_D3497nuc_PP2Bnuc_off"   (PP1nuc_D3497nuc_PP2Bnuc → PP1nuc_D3497nuc + PP2Bnuc)
    • Reaction "D3497nuc_PP2Bnuc_on"   (D3497nuc + PP2Bnuc → D3497nuc_PP2Bnuc)
    • Reaction "D34nuc_CK2_cat"   (D34nuc_CK2 → CK2 + D3497nuc)
    • Reaction "Dnuc_CK2_off"   (Dnuc_CK2 → Dnuc + CK2)
    • Reaction "Dnuc_PKAnuc_cat"   (Dnuc_PKAnuc → D34nuc + PKAnuc)
    • Reaction "D97nuc_PKAnuc_on"   (D97nuc + PKAnuc → D97nuc_PKAnuc)
    • Reaction "D34nuc_PP2Bnuc_on"   (D34nuc + PP2Bnuc → D34nuc_PP2Bnuc)
    • Reaction "PP2Anuc_PKAnuc_on"   (PP2Anuc + PKAnuc → PP2Anuc_PKAnuc)
    • Reaction "PP1nuc_D3497nuc_PP2Bnuc_on"   (PP2Bnuc + PP1nuc_D3497nuc → PP1nuc_D3497nuc_PP2Bnuc)
    • Reaction "PP1nuc_D34nuc_PP2Bnuc_cat"   (PP1nuc_D34nuc_PP2Bnuc → PP1nuc + Dnuc + PP2Bnuc)
    • Reaction "PP1nuc_D34nuc_on"   (D34nuc + PP1nuc → PP1nuc_D34nuc)
    • Reaction "Dnuc_CK2_on"   (Dnuc + CK2 → Dnuc_CK2)
    • Reaction "D3497nuc_PP2Apnuc_cat"   (D3497nuc_PP2Apnuc → D34nuc + PP2Apnuc)
    • Reaction "D34nuc_PP2Bnuc_cat"   (D34nuc_PP2Bnuc → PP2Bnuc + Dnuc)
    • Reaction "D3497nuc_PP2Apnuc_on"   (D3497nuc + PP2Apnuc → D3497nuc_PP2Apnuc)
    • Reaction "Dnuc_PKAnuc_on"   (PKAnuc + Dnuc → Dnuc_PKAnuc)
    • Reaction "D34nuc_CK2_off"   (D34nuc_CK2 → CK2 + D34nuc)
    • Reaction "PP1nuc_D34nuc_PP2Bnuc_off"   (PP1nuc_D34nuc_PP2Bnuc → PP1nuc_D34nuc + PP2Bnuc)
    • Reaction "D34nuc_PP2Bnuc_off"   (D34nuc_PP2Bnuc → PP2Bnuc + D34nuc)
    • Reaction "D3497nuc_PP2Bnuc_cat"   (D3497nuc_PP2Bnuc → PP2Bnuc + D97nuc)
    • Reaction "D34nuc_CK2_on"   (D34nuc + CK2 → D34nuc_CK2)
    • Reaction "D97nuc_PP2Apnuc_off"   (D97nuc_PP2Apnuc → PP2Apnuc + D97nuc)
    • Reaction "PP2Anuc_PKANuc_off"   (PP2Anuc_PKAnuc → PP2Anuc + PKAnuc)
    • Reaction "PP1nuc_D34nuc_PP2Bnuc_on"   (PP1nuc_D34nuc + PP2Bnuc → PP1nuc_D34nuc_PP2Bnuc)
    • Reaction "D97nuc_PP2Apnuc_on"   (PP2Apnuc + D97nuc → D97nuc_PP2Apnuc)
    • Reaction "D3497nuc_PP2Bnuc_off"   (D3497nuc_PP2Bnuc → D3497nuc + PP2Bnuc)
    • Reaction "D3497nuc_PP2Apnuc_off"   (D3497nuc_PP2Apnuc → PP2Apnuc + D3497nuc)
    • Reaction "PP2Apnucdephosphorylation"   (PP2Apnuc → PP2Anuc)
    • Reaction "PP1nuc_D3497nuc_on"   (D3497nuc + PP1nuc → PP1nuc_D3497nuc)
    • Reaction "Dnuc_PKAnuc_off"   (Dnuc_PKAnuc → PKAnuc + Dnuc)
    • Reaction "D97nuc_PKAnuc_off"   (D97nuc_PKAnuc → D97nuc + PKAnuc)
  • Compartment "cellmembrane".   (type: Membrane)
  • Compartment "nucleusmembrane".   (type: Membrane)
    • Reaction "PP1cyto_D34cyto_PP2Bcyto_cyto2nuc"   (PP1cyto_D34cyto_PP2Bcyto → PP1nuc_D34nuc_PP2Bnuc)
    • Reaction "PP2Apcyto2nuc"   (PP2Apcyto → PP2Apnuc)
    • Reaction "PP1cyto_D3497cyto_PP2Bcyto_cyto2nuc"   (PP1cyto_D3497cyto_PP2Bcyto → PP1nuc_D3497nuc_PP2Bnuc)
    • Reaction "D97nuc2cyto"   (D97nuc → D97cyto)
    • Reaction "Dcyto2nuc_passive"   (Dcyto → Dnuc)
    • Reaction "D34cyto2nuc_passive"   (D34cyto → D34nuc)
    • Reaction "PP1nuc_D34nuc_nuc2cyto"   (PP1nuc_D34nuc → PP1cyto_D34cyto)
    • Reaction "D3497nuc2cyto"   (D3497nuc → D3497cyto)
    • Reaction "D3497cyto2nuc"   (D3497cyto → D3497nuc)
    • Reaction "D3497nuc2cyto_passive"   (D3497nuc → D3497cyto)
    • Reaction "PP2Anuc2cyto"   (PP2Anuc → PP2Acyto)
    • Reaction "Dnuc2cyto_passive"   (Dnuc → Dcyto)
    • Reaction "D3497cyto_PP2Bcyto_cyto2nuc"   (D3497cyto_PP2Bcyto → D3497nuc_PP2Bnuc)
    • Reaction "PP2Bnuc2cyto"   (PP2Bnuc → PP2Bcyto)
    • Reaction "D97cyto_PP2Apcyto_cyto2nuc"   (D97cyto_PP2Apcyto → D97nuc_PP2Apnuc)
    • Reaction "PP1cyto_D34cyto_cyto2nuc"   (PP1cyto_D34cyto → PP1nuc_D34nuc)
    • Reaction "D3497nuc_PP2Bnuc_nuc2cyto"   (D3497nuc_PP2Bnuc → D3497cyto_PP2Bcyto)
    • Reaction "Dcyto2nuc"   (Dcyto → Dnuc)
    • Reaction "D97nuc_PKAnuc_nuc2cyto"   (D97nuc_PKAnuc → D97cyto_PKAcyto)
    • Reaction "PKAnuc2cyto"   (PKAnuc → PKAcyto)
    • Reaction "PP1cyto2nuc"   (PP1cyto → PP1nuc)
    • Reaction "PP1nuc_D3497nuc_PP2Bnuc_nuc2cyto"   (PP1nuc_D3497nuc_PP2Bnuc → PP1cyto_D3497cyto_PP2Bcyto)
    • Reaction "PP2Anuc_PKAnuc_nuc2cyto"   (PP2Anuc_PKAnuc → PP2Acyto_PKAcyto)
    • Reaction "D34cyto_PP2Bcyto_cyto2nuc"   (D34cyto_PP2Bcyto → D34nuc_PP2Bnuc)
    • Reaction "D97nuc2cyto_passive"   (D97nuc → D97cyto)
    • Reaction "Dcyto_PKAcyto_cyto2nuc"   (Dcyto_PKAcyto → Dnuc_PKAnuc)
    • Reaction "PP2Apnuc2cyto"   (PP2Apnuc → PP2Apcyto)
    • Reaction "PKAcyto2nuc"   (PKAcyto → PKAnuc)
    • Reaction "PP2Acyto_PKAcyto_cyto2nuc"   (PP2Acyto_PKAcyto → PP2Anuc_PKAnuc)
    • Reaction "D97nuc_PP2Apnuc_nuc2cyto"   (D97nuc_PP2Apnuc → D97cyto_PP2Apcyto)
    • Reaction "PP2Bcyto2nuc"   (PP2Bcyto → PP2Bnuc)
    • Reaction "D34cyto2nuc"   (D34cyto → D34nuc)
    • Reaction "PP2Acyto2nuc"   (PP2Acyto → PP2Anuc)
    • Reaction "PP1nuc2cyto"   (PP1nuc → PP1cyto)
    • Reaction "D97cyto2nuc_passive"   (D97cyto → D97nuc)
    • Reaction "PP1cyto_D3497cyto_cyto2nuc"   (PP1cyto_D3497cyto → PP1nuc_D3497nuc)
    • Reaction "PP1nuc_D3497nuc_nuc2cyto"   (PP1nuc_D3497nuc → PP1cyto_D3497cyto)
    • Reaction "D3497cyto2nuc_passive"   (D3497cyto → D3497nuc)
    • Reaction "D34nuc2cyto_passive"   (D34nuc → D34cyto)
    • Reaction "D97cyto_PKAcyto_cyto2nuc"   (D97cyto_PKAcyto → D97nuc_PKAnuc)
    • Reaction "D97cyto2nuc"   (D97cyto → D97nuc)
    • Reaction "D3497cyto_PP2Apcyto_cyto2nuc"   (D3497cyto_PP2Apcyto → D3497nuc_PP2Apnuc)
    • Reaction "D3497nuc_PP2Apnuc_nuc2cyto"   (D3497nuc_PP2Apnuc → D3497cyto_PP2Apcyto)
2018-07-12T19:23:23+00:00 February 16th, 2018|biomodel|