Name: “eungdamrong and Iyengar BiophysJ”
Saved: Mon, 21 Aug 2006  14:34:08 GMT
vcell identifier: biomodel-18894555
Owned by: “eungdamr”

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Compartments, Species, Reactions
  • Compartment "EC".   (type: Volume)
    • Species "EGF_EC"
  • Compartment "cyt".   (type: Volume)
    • Species "CAPRI_cyt"
    • Species "RasGTP_pal_cyt"
    • Species "Ca"
    • Species "IP3"
    • Species "CaCAPRI_cyt"
    • Species "RasGTP_depal_cyt"
    • Species "RasGDP_depal_cyt"
    • Species "RasGDP_pal_cyt"
    • Species "Ca_PLCe_cyt"
    • Species "Sos_cyt"
    • Species "Grb2_cyt"
    • Species "PLCe_cyt"
    • Species "buffer_cyt"
    • Species "ca_buffer_cyt"
    • Species "SosGrb2_cyt"
    • Species "RasGRP_cyt"
    • Species "CaRasGRP1_cyt"
    • Reaction "Ca bind CAPRI"   (Ca + CAPRI_cyt → CaCAPRI_cyt)
    • Reaction "IP3 degradation"   (IP3 → ∅)
    • Reaction "ca bind rasGRP"   (Ca + RasGRP_cyt → CaRasGRP1_cyt)
    • Reaction "sos grb2 binding"   (Sos_cyt + Grb2_cyt → SosGrb2_cyt)
    • Reaction "RasPal basal GAP"   (RasGTP_pal_cyt → RasGDP_pal_cyt)
    • Reaction "basal cyt depal GEF"   (RasGTP_depal_cyt → RasGDP_depal_cyt)
    • Reaction "calcium buffer"   (buffer_cyt + Ca → ca_buffer_cyt)
    • Reaction "ca act PLCe"   (Ca + PLCe_cyt → Ca_PLCe_cyt)
  • Compartment "er".   (type: Volume)
    • Species "Ca_ER"
  • Compartment "Golgi".   (type: Volume)
  • Compartment "PM".   (type: Membrane)
    • Species "PIP_PM"
    • Species "PI_PM"
    • Species "Shc_PM"
    • Species "CaCAPRI_PM_PM"
    • Species "Shc_star_PM"
    • Species "EGFR_PM"
    • Species "PLC_act_PM"
    • Species "PLC_PM"
    • Species "PIP2_PM"
    • Species "Activated_EGFR_PM"
    • Species "DAG_PM"
    • Species "SGS_PM"
    • Species "RasGTP_PM"
    • Species "RasGDP_PM"
    • Reaction "PIP2 synthesis"   (PIP_PM → PIP2_PM)
    • Reaction "Shc phosphorylation"   (Shc_PM → Shc_star_PM)
    • Reaction "rasGTP pal translocation"   (RasGTP_pal_cyt → RasGTP_PM)
    • Reaction "PLCg dephos"   (PLC_act_PM → PLC_PM)
    • Reaction "basal GAP"   (RasGTP_PM → RasGDP_PM)
    • Reaction "CAPRI translocation"   (CaCAPRI_cyt → CaCAPRI_PM_PM)
    • Reaction "CAPRI GAP"   (RasGTP_PM → RasGDP_PM)
    • Reaction "RasGDPpal translocation"   (RasGDP_pal_cyt → RasGDP_PM)
    • Reaction "PIP2 hydrolysis"   (PIP2_PM → DAG_PM + IP3)
    • Reaction "Sos activation"   (SosGrb2_cyt + Shc_star_PM → SGS_PM)
    • Reaction "PIP synthesis"   (PI_PM → PIP_PM)
    • Reaction "EGF_internalization "   (Activated_EGFR_PM → ∅)
    • Reaction "reaction0"   (Shc_star_PM → Shc_PM)
    • Reaction "EGFR_binding"   (EGF_EC + EGFR_PM → Activated_EGFR_PM)
    • Reaction "RasGDP depal2"   (RasGDP_PM → RasGDP_depal_cyt)
    • Reaction "EGF act PLCgamma"   (PLC_PM → PLC_act_PM)
    • Reaction "Sos act RasPM"   (RasGDP_PM → RasGTP_PM)
    • Reaction "Ras PM depal1"   (RasGTP_PM → RasGTP_depal_cyt)
  • Compartment "erMembrane".   (type: Membrane)
    • Species "serca"
    • Species "RactCa"
    • Species "Ract"
    • Species "Rinh"
    • Species "RinhCa"
    • Species "ER_erMembrane"
    • Reaction "reaction2"   (Rinh + Ca → RinhCa)
    • Reaction "Ca_binds_IP3R"   (Ract + Ca → RactCa)
    • Reaction "flux1"   (Ca → Ca_ER)
    • Reaction "flux0"   (Ca → Ca_ER)
    • Reaction "flux2"   (Ca → Ca_ER)
  • Compartment "GM".   (type: Membrane)
    • Species "RasGTP_Golgi_GM"
    • Species "RasGDP_Golgi_GM"
    • Species "Ca_RasGRP_GM_GM"
    • Species "DAG_GM_GM"
    • Species "RasGRP_DAG_GM"
    • Species "Ras_CaPLCe_GM"
    • Species "PIP2_GM_GM"
    • Reaction "RasGTP depal translocate"   (RasGTP_depal_cyt → RasGTP_Golgi_GM)
    • Reaction "RasGRP_DAG GEF "   (RasGDP_Golgi_GM → RasGTP_Golgi_GM)
    • Reaction "reaction5"   (DAG_GM_GM + RasGRP_cyt → RasGRP_DAG_GM)
    • Reaction "RasGDP pal"   (RasGDP_Golgi_GM → RasGDP_pal_cyt)
    • Reaction "RasGDP depal translocate"   (RasGDP_depal_cyt → RasGDP_Golgi_GM)
    • Reaction "Ras GTP palm1"   (RasGTP_Golgi_GM → RasGTP_pal_cyt)
    • Reaction "caPLCe gen DAG"   (PIP2_GM_GM → DAG_GM_GM + IP3)
    • Reaction "CaRasGRP act RasGM"   (RasGDP_Golgi_GM → RasGTP_Golgi_GM)
    • Reaction "RasGM basal GAP"   (RasGTP_Golgi_GM → RasGDP_Golgi_GM)
    • Reaction "ras_act_PLCe"   (RasGTP_Golgi_GM + Ca_PLCe_cyt → Ras_CaPLCe_GM)
    • Reaction "CaRasGRP translocation"   (CaRasGRP1_cyt → Ca_RasGRP_GM_GM)
    • Reaction "reaction7"   (DAG_GM_GM → ∅)
2018-07-12T19:23:14+00:00 February 16th, 2018|biomodel|