biomodel-66264973

Name: “Brown et al 2011 Analysis of SCA1-SCA2-SCA3 with IC-G2736X Peptide”
Saved: Wed, 30 May 2012  12:38:18 GMT
vcell identifier: biomodel-66264973
Owned by: “Brown”

download model (.vcml)

• Compartment "ER".   (type: Volume)
  • Species "Ca_ER"
• Compartment "Extracellular".   (type: Volume)
  • Species "Ca_Extracellular"
  • Species "Ca_D_Extracellular"
• Compartment "spine".   (type: Volume)
  • Species "ICpeptide_mAtaxin1_spine"
  • Species "ICpeptide_spine"
  • Species "IP3_spine"
  • Species "mAtaxin1_spine"
  • Species "PP1a_spine"
  • Species "Ca_spine"
  • Species "ICpeptide_PP1a_spine"
  • Species "CG_spine"
  • Species "CGB_spine"
  • Species "D28kB_spine"
  • Species "D28kB_D_spine"
  • Species "r_neck_spine"
  • Species "r_spine_spine"
  • Species "l_neck_spine"
  • Species "D28k_high_D_spine"
  • Species "D28k_high_spine"
  • Species "PABCa_D_spine"
  • Species "PABCa_spine"
  • Species "PA_spine"
  • Species "IP3_D_spine"
  • Species "CGB_D_spine"
  • Species "Mg_spine"
  • Species "Ca_D_spine"
  • Species "D28kB_high_D_spine"
  • Species "PABMg_D_spine"
  • Species "PA_D_spine"
  • Species "D28k_spine"
  • Species "D28kB_high_spine"
  • Species "D28k_D_spine"
  • Species "CG_D_spine"
  • Species "Mg_D_spine"
  • Species "PABMg_spine"
  • Reaction "D28k_d"   (D28k_spine → ∅)
  • Reaction "CGB_d"   (CGB_spine → ∅)
  • Reaction "PABCa_d"   (PABCa_spine → ∅)
  • Reaction "CG_deg"   (CG_D_spine → ∅)
  • Reaction "D28kB_deg"   (D28kB_D_spine → ∅)
  • Reaction "PABCa_deg"   (PABCa_D_spine → ∅)
  • Reaction "CD28k_high"   (Ca_spine + D28k_high_spine → D28kB_high_spine)
  • Reaction "D28kBDbinding"   (D28k_D_spine + Ca_D_spine → D28kB_D_spine)
  • Reaction "CG_Dbinding"   (Ca_D_spine + CG_D_spine → CGB_D_spine)
  • Reaction "PA_deg"   (PA_D_spine → ∅)
  • Reaction "D28kB_high_deg"   (D28kB_high_D_spine → ∅)
  • Reaction "Ca_d"   (Ca_spine → ∅)
  • Reaction "CG_d"   (CG_spine → ∅)
  • Reaction "PA_MgD"   (Mg_D_spine + PA_D_spine → PABMg_D_spine)
  • Reaction "IP3_degr"   (IP3_spine → ∅)
  • Reaction "D28kB_high_d"   (D28kB_high_spine → ∅)
  • Reaction "D28k_deg"   (D28k_D_spine → ∅)
  • Reaction "PA_d"   (PA_spine → ∅)
  • Reaction "IP3deg"   (IP3_D_spine → ∅)
  • Reaction "CGbinding"   (Ca_spine + CG_spine → CGB_spine)
  • Reaction "PP1a bind ICpeptide"   (PP1a_spine + ICpeptide_spine → ICpeptide_PP1a_spine)
  • Reaction "mAtaxin1 bind ICpeptide"   (mAtaxin1_spine + ICpeptide_spine → ICpeptide_mAtaxin1_spine)
  • Reaction "D28kB_d"   (D28kB_spine → ∅)
  • Reaction "D28k_high_deg"   (D28k_high_D_spine → ∅)
  • Reaction "pulses"   (∅ → IP3_spine)
  • Reaction "CGB_deg"   (CGB_D_spine → ∅)
  • Reaction "PA_Mg"   (PA_spine + Mg_spine → PABMg_spine)
  • Reaction "CD28k_highDbinding"   (Ca_D_spine + D28k_high_D_spine → D28kB_high_D_spine)
  • Reaction "PABMg_deg"   (PABMg_D_spine → ∅)
  • Reaction "Ca_deg"   (Ca_D_spine → ∅)
  • Reaction "PA_Dbinding"   (PA_D_spine + Ca_D_spine → PABCa_D_spine)
  • Reaction "CaD28k_med"   (D28k_spine + Ca_spine → D28kB_spine)
  • Reaction "IP3_d"   (IP3_spine → ∅)
  • Reaction "D28k_high_d"   (D28k_high_spine → ∅)
  • Reaction "PABMg_d"   (PABMg_spine → ∅)
  • Reaction "PA_Ca"   (PA_spine + Ca_spine → PABCa_spine)
  • Reaction "IP3_degr1"   (IP3_D_spine → ∅)
• Compartment "SM".   (type: Membrane)
  • Reaction "flux0"   (Ca_Extracellular → Ca_spine)
  • Reaction "flux1"   (Ca_D_Extracellular → Ca_D_spine)
• Compartment "ER_SM".   (type: Membrane)
  • Species "ERDensity_ER_SM"
  • Species "IP3R1_Ct_ER_SM"
  • Species "IP3R1_Ct_PP1a_ER_SM"
  • Species "IP3R1_Ct_mAtaxin_ER_SM"
  • Species "h_ER_SM"
  • Reaction "PP1a bind ICt"   (IP3R1_Ct_ER_SM + PP1a_spine → IP3R1_Ct_PP1a_ER_SM)
  • Reaction "mAtaxin1 bind ICt"   (IP3R1_Ct_ER_SM + mAtaxin1_spine → IP3R1_Ct_mAtaxin_ER_SM)
  • Reaction "reaction0"   (h_ER_SM → ∅)
  • Reaction "IP3R_flux"   (Ca_spine → Ca_ER)
  • Reaction "SERCA_flux"   (Ca_spine → Ca_ER)
  • Reaction "ER_leak_flux"   (Ca_spine → Ca_ER)