Name: “Khalilimeybodi et al. 2022 J Physiol”
Saved: Mar 15, 2024
vcell identifier: biomodel-269930396
Owned by: “prangamani”

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Compartments, Species, Reactions
  • Compartment "ECM".   (type: Volume)
    • Species "Ca_Ext"
    • Species "Ligand"
    • Species "TG"
  • Compartment "Cyto".   (type: Volume)
    • Species "Fakp"
    • Species "RhoAGDP"
    • Species "Fak"
    • Species "ROCK_S"
    • Species "ROCK"
    • Species "mDia"
    • Species "mDia_S"
    • Species "Myo"
    • Species "Myo_S"
    • Species "LIMK"
    • Species "CofilinP"
    • Species "LIMK_S"
    • Species "Cofilin"
    • Species "F_actin"
    • Species "G_actin"
    • Species "YAPTAZcP"
    • Species "YAPTAZc"
    • Species "Ca_Cyt"
    • Species "IP3"
    • Species "DAG"
    • Species "cPKC"
    • Species "cPKC_Ca"
    • Species "cPKC_Ca_DAG"
    • Species "nPKC"
    • Species "nPKC_DAG"
    • Species "LATS12"
    • Species "LATS12_P"
    • Species "MST12"
    • Species "cPKC_Ca_DAG_S"
    • Species "MST12P"
    • Species "aPKC"
    • Species "AKTPP"
    • Species "AKT"
    • Species "JNK"
    • Species "JNK_p"
    • Species "Pyk2"
    • Species "Pyk2_p"
    • Species "Buffercyt"
    • Species "Buffercyt_Ca"
    • Species "CaM"
    • Species "CaMKII"
    • Species "CaMKIIP"
    • Species "Arp23"
    • Species "Arp23_S"
    • Species "Ca_CaM"
    • Species "TGS"
    • Species "TGSm"
    • Species "PP2Ac"
    • Species "PP2Ac_S"
    • Species "Merlin"
    • Species "Merlin_S"
    • Reaction "R39"   (ROCK_S → ROCK)
    • Reaction "R43"   (LIMK → LIMK_S)
    • Reaction "R51"   (Myo → Myo_S)
    • Reaction "R44"   (CofilinP → Cofilin)
    • Reaction "R42"   (G_actin → F_actin)
    • Reaction "R41"   (mDia_S → mDia)
    • Reaction "R55"   (YAPTAZcP → YAPTAZc)
    • Reaction "R35"   (Fakp → Fak)
    • Reaction "R33"   (Fak → Fakp)
    • Reaction "R16"   (IP3 → ∅)
    • Reaction "R17"   (DAG → ∅)
    • Reaction "R30"   (Ca_Cyt + cPKC → cPKC_Ca)
    • Reaction "R31"   (DAG + cPKC_Ca → cPKC_Ca_DAG)
    • Reaction "R29"   (nPKC + DAG → nPKC_DAG)
    • Reaction "R32"   (cPKC_Ca_DAG → cPKC_Ca_DAG_S)
    • Reaction "R47"   (MST12 → MST12P)
    • Reaction "R22"   (AKT → AKTPP)
    • Reaction "R26"   (JNK → JNK_p)
    • Reaction "R28"   (Pyk2 → Pyk2_p)
    • Reaction "R20"   (Ca_Cyt + Buffercyt → Buffercyt_Ca)
    • Reaction "R24"   (CaMKII → CaMKIIP)
    • Reaction "R25"   (CaMKIIP → CaMKII)
    • Reaction "R46"   (Arp23 → Arp23_S)
    • Reaction "R54"   (YAPTAZc → YAPTAZcP)
    • Reaction "R21"   (Ca_Cyt + CaM → Ca_CaM)
    • Reaction "R58"   (TGS → TGSm)
    • Reaction "R57"   (PP2Ac → PP2Ac_S)
    • Reaction "R23"   (AKTPP → AKT)
    • Reaction "R27"   (JNK_p → JNK)
    • Reaction "R48"   (MST12P → MST12)
    • Reaction "R45"   (Merlin → Merlin_S)
    • Reaction "R50"   (LATS12_P → LATS12)
    • Reaction "R49"   (LATS12 → LATS12_P)
  • Compartment "Nuc".   (type: Volume)
    • Species "YAPTAZnuc"
  • Compartment "ER".   (type: Volume)
    • Species "Ca_ER"
  • Compartment "NM".   (type: Membrane)
    • Species "NPC_S"
    • Species "NPC"
    • Species "LaminA"
    • Species "LaminAp"
    • Reaction "R53"   (NPC → NPC_S)
    • Reaction "R52"   (LaminAp → LaminA)
    • Reaction "R56"   (YAPTAZc → YAPTAZnuc)
  • Compartment "PM".   (type: Membrane)
    • Species "RhoAGTP_MEM"
    • Species "L_GR"
    • Species "GR"
    • Species "GqGDP"
    • Species "L_GR_GqGDP"
    • Species "GR_GqGDP"
    • Species "GqGTP"
    • Species "L_GR_GqGDP_P"
    • Species "PLCB"
    • Species "PLCB_GqGTP"
    • Species "PLCB_Ca"
    • Species "PLCB_Ca_GqGTP"
    • Species "PIP2"
    • Species "PA"
    • Reaction "R37"   (RhoAGTP_MEM → RhoAGDP)
    • Reaction "R38"   (ROCK → ROCK_S)
    • Reaction "R40"   (mDia → mDia_S)
    • Reaction "R34"   (Fak → Fakp)
    • Reaction "R36"   (RhoAGDP → RhoAGTP_MEM)
    • Reaction "R1"   (Ligand + GR → L_GR)
    • Reaction "R2"   (GqGDP + L_GR → L_GR_GqGDP)
    • Reaction "R3"   (GqGDP + GR → GR_GqGDP)
    • Reaction "R4"   (Ligand + GR_GqGDP → L_GR_GqGDP)
    • Reaction "R5"   (L_GR_GqGDP → L_GR + GqGTP)
    • Reaction "R6"   (L_GR_GqGDP → L_GR_GqGDP_P)
    • Reaction "R7"   (GqGTP → GqGDP)
    • Reaction "R8"   (PLCB + GqGTP → PLCB_GqGTP)
    • Reaction "R9"   (PLCB + Ca_Cyt → PLCB_Ca)
    • Reaction "R10"   (GqGTP + PLCB_Ca → PLCB_Ca_GqGTP)
    • Reaction "R11"   (Ca_Cyt + PLCB_GqGTP → PLCB_Ca_GqGTP)
    • Reaction "R12"   (PLCB_Ca_GqGTP → GqGDP + PLCB_Ca)
    • Reaction "R13"   (PLCB_GqGTP → GqGDP + PLCB)
    • Reaction "R15"   (PIP2 → IP3 + DAG)
    • Reaction "R14"   (PIP2 → DAG + IP3)
    • Reaction "R19"   (PA → DAG)
    • Reaction "R18"   (∅ → PA)
    • Reaction "R6S"   (L_GR_GqGDP_P → Ligand + GR + GqGDP)
    • Reaction "TRP"   (Ca_Ext → Ca_Cyt)
    • Reaction "PMCA"   (Ca_Ext → Ca_Cyt)
    • Reaction "SOCE"   (Ca_Ext → Ca_Cyt)
    • Reaction "PM_leak"   (Ca_Ext → Ca_Cyt)
  • Compartment "ERM".   (type: Membrane)
    • Reaction "ER_leak"   (Ca_Cyt → Ca_ER)
    • Reaction "IP3R"   (Ca_Cyt → Ca_ER)
    • Reaction "Serca_flux"   (Ca_Cyt → Ca_ER)
2024-03-17T02:26:06+00:00 February 16th, 2023|biomodel|