About Susan Krueger

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So far Susan Krueger has created 9 blog entries.

18th Annual VCell Short Course

June 15th, 2017|News|

VCell was pleased and honored to host its 18th annual VCell Short Course on June 12-14, 2017. Twelve national and international scientists traveled to work with VCell developers and administrators to construct Virtual Cell models based on their own, personal research interests. Thanks to all for a successful time!

SpringSaLaD Update

January 8th, 2017|News|

Update released August 4, 2016. It fixes a minor bug in cluster size statistics. Go to CCAM Software to replace your current version.

VCell 3-day course June 20-22, 2016

June 9th, 2016|News, VCell Posts|

12 investigators traveled to CCAM to work with the VCell team, developing a model relevant to their specific research project.



New VCell model of blood coagulation factors

June 9th, 2016|News, VCell Posts|

2016 -06-09  Hysteresis-like binding of coagulation factors x/xa to procoagulant activated platelets and phospholipids results from multistep association and membrane-dependent multimerization (Podoplelova et al. 2016. Biochim Biophys Acta. 1858:1216-1227. PMID 26874201).  Find the public BioModel here.

New VCell Model from the Hille lab

June 9th, 2016|News, VCell Posts|

VCell models were used to quantitatively analyze FRET measurements were used to demonstrate that voltage-sensing phosphatases (VSPs) have catalytic activity for PIP3 (Keum et al. 2016.  Phosphoinositide 5- and 3-phosphatase activities of a voltage-sensing phosphatase in living cells show identical voltage dependence. Proc Natl Acad Sci U S A. 10.1073/pnas.1606472113, PMID 27222577).  Find the public VCell model here.

New VCell model of G-protein coupled receptors

June 9th, 2016|News, VCell Posts|

2016-05-03  A new model of pancreatic beta cell G-protein coupled receptors and second messenger interactions was recently published in PLoS One by Fridlyand and Philipson. Go to our Published Models listing to link to the publication and view details of the model.

New published VCell Model of protease-activated receptor 2 signaling.

June 8th, 2016|News, VCell Posts|

2016-03-01.   A new publication describes a VCell model that evaluates the contributions of protein kinases and beta-arrestin to termination of protease-activated receptor 2 signaling. Visit the Published Models page for details and links to the publication.

New method for particle-based simulations with excluded volume.

June 8th, 2016|News, VCell Posts|

2016-02-02  SpringSaLad (Springs, Sites, and Langevin Dynamics) is a new software that uses a course-grained approach to model biomolecules as a group of linked spherical sites with excluded volumes.  The software user material is available here.  Read about the method and software in  Springsalad: A spatial, particle-based biochemical simulation platform with excluded volume. Michalski, P.J., and L.M. Loew. 2016 Biophys J. 110:523-529. PMID 26840718.

New VCell Model of phosphoinositide signaling

June 8th, 2016|News, VCell Posts|

2016-06-08  A new VCell Model from the Hille lab describes the dynamics of phosphoinositide signaling in sympathetic neurons.   Details of the model and links to the publication can be found on our Published Models listing.