VCell model of Mad signaling

2021-04-16T14:03:55+00:00 March 30th, 2021|News|

2021-3-30. A new paper from the Inaba lab uses a VCell model to explore how pMad is asymmetrically partitioned to forming daughter nuclei during division of stem cells in the Drosophila ovary.  Find links to the model and citation on our published models page.

VCell 7.4 released

2021-03-23T15:22:09+00:00 March 23rd, 2021|News|

2021-03-23.VCell 7.4 has been released.  New in VCell 7.4 is the ability to preview geometries from the VCell database, vastly accelerated multiple trajectory stochastic simulations using the Gibson-Bruck solver, extension of unit display and automatic conversion to rate and assignment rules, support for external access to containerized versions of some VCell solvers with command line execution, as well as numerous additional improvements and bug fixes.

New VCell model of Ras signaling

2021-04-02T17:34:45+00:00 March 18th, 2021|News|

2021-3-18. A new paper by Kerbai Eroume in the Carlier lab published in PLOS One explores how cell shape affects the signaling mechanisms that determine cell polarization. Find links to the model and citation on our published models page.

VCell 7.3 released

2020-12-07T15:37:30+00:00 November 30th, 2020|News|

2020-11-30. Announcing the release of VCell 7.3!  VCell 7.3 adds capabilities for multiple trajectories for non-spatial stochastic simulationss, interchange with the Open Modeling EXchange format (.omex), and automatic assignment of catalysts in the reaction diagram as well as numerous additional improvements and bug fixes.

VCell model of Ca-cAMP-PKA

2021-04-02T17:29:00+00:00 November 17th, 2020|News|

2020-11-17. A VCell model was used to explore Ca2+-cAMP-PKA signalling circuits in a new publication from the Rangamani and Zhang laboratories. Find links to the model and citation on our published models page.

VCell model of agonist-induced signaling

2020-12-08T15:26:47+00:00 November 16th, 2020|News|

2020-11-16. A new publication from the Lambert lab investigates the mechanisms that set the dynamic range of agonist-induced signaling using fluorescence imaging coupled with VCell modeling.   Visit our published models page for links to the paper and to access the VCell model.

New VCell model of Ras signaling copy

2021-04-05T15:07:22+00:00 November 3rd, 2020|News|

2020-9-3. A new VCell model created incollaboration between the McCulloch and Zhang labs helped to demonstrate that a second phase of RhoA activation is required to maintain RhoA-mediated transcription after receptor signalling ends. Find links to the model and paper by Zhang et al. on our published models page.

2020 CompCellBio Workshop

2020-08-17T13:34:37+00:00 August 6th, 2020|News|

2020-08-05. The 2020 Computational Cell Biology Workshop was held as an online event Aug 3-5.  Find videos of the key presentations here.  Over 70 individuals participated overall; 16 individuals created models with VCell, COPASI and SpringSaLaD with help from CCAM team members in breakout rooms.  A screen shot of one the opening day presentations serves in place of our traditional group photo this year.