2020-10-20. A new publication from the Rangamani and Iyengar labs using VCell modeling to explore how cell shape affects calcium dynamics in vascular smooth muscle cells. Visit our published models page for links to the paper.
2020-08-05. The 2020 Computational Cell Biology Workshop was held as an online event Aug 3-5. Find videos of the key presentations here. Over 70 individuals participated overall; 16 individuals created models with VCell, COPASI and SpringSaLaD with help from CCAM team members in breakout rooms. A screen shot of one the opening day presentations serves in place of our traditional group photo this year.
2020-07-10. A new publication analyzes fluorescence photobleaching experiments using VCell numerical simulations to explore mechanisms of for differentiating somatodendritic and axonal compartments. Visit our published models page for links to the paper.
2020-04-07. A new spatial model of the PLC/PKC pahtway created in VCell was used to explore chemotactic sensing in fibroblasts in a new publication by Nosbisch et al from the Haugh lab. Visit our published models page for links to the paper and the VCell model.
2020-03-09. A new VCell model is used to explore how MYB proteins form an activator-inhibitor system that defines the spot pattern in mokeyflower petals. Visit our published models page for links to the paper and the VCell model.
2020-01-30. A VCell model is used in a new paper by Dreyer and Michard to re-examine the concept of high- and low-affinity nutrient uptade systems in plants. Visit our published models page for links to the paper.
2019-12-10. VCell 7.2 has been released. See the Release Notes for a full list of the many new features in VCell 7.2 including new functionality to store identifiers and text annotations for model components, a service linking VCell simulation with ImageJ image analysis functions, rate rules and assignment rules in ODE applications, improved SBML import along with several other improvements.
2019-11-28. VCell was used to create a 2D spatial model of cAMP intracellular signaling in a new publication by Stone and colleagues. Visit our published models page for links to the paper.
2019-6-18 CCAM hosted a Computational Cell Biology Workshop on June 24-26, 2019, a combined workshop for both VCell and COPASI modeling software. Ten scientists from the US, Netherlands and Germany traveled to work with the VCell and COPASI teams to construct models based on their own research interests. It was exciting to see VCell and COPASI models applied to such interesting cell biology projects. Thanks to all for a very successful course!
2019-06-13. A new Molecular Biology of the Cell publication from the Rangamani lab uses VCell and COPASI to develop a model to examine cross-talk between receptor tyrosine kinases and G proteins that regulate cAMP levels. Visit our published models page for links to the paper and to the VCell Biomodel.
