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So far acowan has created 108 blog entries.

New model of Sperm Calcium

2021-09-03T14:31:58+00:00 July 28th, 2021|News|

2021-7-27. A new VCell model by Korobkin et al, explores calcium oscillations in mammalian sperm. COPASI software was also utilized for parameter estimation to fit the models.   Find links to the paper and public VCell models on our published models page.

2021 Computational Cell Biology Workshop help June 21-23.

2021-08-17T19:31:49+00:00 June 24th, 2021|News, VCell Posts|

2021-6-24  CCAM’s annual Computational Cell Biology Workshop was again held online June 21-23, 2021.  The workshop provided instruction to over 50 individuals from around the world on mathematical modeling techniques using VCell, COPASI and SpringSaLaD software. Fifteen of the participants worked closely with CCAM researchers to develop their own models related to their research projects. Another successful year for the modeling workshop! a combined workshop for VCell, COPASI, and SpringSaLaD modeling software. Thanks to all […]

VCell model of YAP/TAZ

2021-08-17T19:33:40+00:00 May 8th, 2021|News|

2021-5-08. A new VCell model from the Rangamani lab explores how YAP/TAZ signaling integrates inputs from different biophysical properties of the cell. Find links to the paper and public VCell models on our published models page.

Scott et al., 2021

2021-08-17T18:37:37+00:00 May 8th, 2021|publication, publication-2021|

A spatial model of YAP/TAZ signaling reveals how stiffness, dimensionality, and shape contribute to emergent outcomes.
Scott, K.E.; Fraley, S.I.;Rangamani, P.
Proc Natl Acad Sci U S A 2021, 118 (20): e2021571118.
PUBMED:33990464
doi:10.1073/pnas.2021571118
VCell BioModels referenced in publication
user: prangamani, biomodel name: Scott_Fraley_Rangamani_YAP_TAZ_model_2021(Rho and FAK confined simulations (true 2D)
user: prangamani, biomodel name: Scott_Fraley_Rangamani_YAP_TAZ_model_2021(2D and 3D simulations)

biomodel-200304683

2021-08-17T15:40:09+00:00 May 7th, 2021|biomodel|

Name: “Scott_Fraley_Rangamani_YAP_TAZ_model_2021(Rho and FAK confined simulations (true 2D)”
Saved: Feb 31, 2021
vcell identifier: biomodel-200301683
Owned by: “prangamani”

download model (.vcml)

Sardi et al., 2021

2021-04-15T19:22:18+00:00 April 15th, 2021|publication, publication-2021|

Mad Dephosphorylation at the Nuclear Pore Is Essential for Asymmetric Stem Cell Division.
Sardi, J.; Bener, M. B.; Simao, T.; Descoteaux, A. E.; Slepchenko, B. M.; Inaba, M.
Proc Natl Acad Sci U S A 2021, 118 (13): e2006786118.
PUBMED:33753475
doi:10.1073/pnas.2006786118
VCell MathModels referenced in publication
user: boris, model name: Inaba_Model_public_final