acowan

Eroume et al., 2021

acowan 2021-10-12T19:36:57+00:00 September 12th, 2021|publication, publication-2021|

Exploring the influence of cytosolic and membrane FAK activation on YAP/TAZ nuclear translocation.
Eroumé KS; Cavill R; Staňková K; de Boer J; Carlier A
Biophys J. 2021 Sep 10;S0006-3495(21)00743–8.
PUBMED:34509508
doi:10.1016/j.bpj.2021.09.009
VCell MathModels referenced in publication
user: kerbai,
Mathmodel names:
Kerbai_BiophysJ_2021_YAPTAZ_Ksf_case3
Kerbai_BiophysJ_2021_YAPTAZ_Ksf_case4
Kerbai_BiophysJ_2021_YAPTAZ_Ksf_case5
Kerbai_BiophysJ_2021_YAPTAZ_noKsf_case1
Kerbai_BiophysJ_2021_YAPTAZ_noKsf_case2
Kerbai_BiophysJ_2021_YAPTAZ_noKsf_case3
Kerbai_BiophysJ_2021_YAPTAZ_noKsf_case4
Kerbai_BiophysJ_2021_YAPTAZ_noKsf_case5

New model of FAK influence on YAP-TAZ

acowan 2021-10-13T19:13:46+00:00 September 10th, 2021|News|

2021-09-10. VCell MathModels were used to explore how FAK activation influences YAP/TAZ translocation in a new publication by Eroume et al. in Biophysical Journal. Find links to the paper and public VCell models on our published models page.

New model of actin filament nucleation

acowan 2021-10-14T18:33:32+00:00 September 9th, 2021|News|

2021-09-9. VCell models and COPASI parameter estimation tools were used to test molecular mechanisms for actin filament nucleation in a paper from the Loew and Pollard labs. Find links to the paper and public VCell models on our published models page.

Rosenbloom et al., 2021

acowan 2021-10-14T18:21:32+00:00 September 9th, 2021|publication, publication-2021|

Mechanism of actin filament nucleation.
Rosenbloom, AD; Kovar, EW; Kovar, DR; Loew, LM; Pollard, TD;
Biophys J. 2021 Sep 10;S0006-3495(21)00740-2
PUBMED:34509503
doi:10.1016/j.bpj.2021.09.006
VCell BioModels referenced in publication
user: AaronRosenbloom, biomodel name: NucleationMechanism

biomodel-217669650

acowan 2021-10-14T16:22:11+00:00 September 9th, 2021|biomodel|

Name: “NucleationMechanism”
Saved: Oct 14, 2021
vcell identifier: biomodel-217669650
Owned by: “AaronRosenbloom”

download model (.vcml)

New model of Sperm Calcium

acowan 2021-09-03T14:31:58+00:00 July 28th, 2021|News|

2021-7-27. A new VCell model by Korobkin et al, explores calcium oscillations in mammalian sperm. COPASI software was also utilized for parameter estimation to fit the models. Find links to the paper and public VCell models on our published models page.

Korobkin et al., 2021

acowan 2021-09-03T14:20:19+00:00 July 27th, 2021|publication, publication-2021|

Occurrence of Calcium Oscillations in Human Spermatozoa Is Based on Spatial Signaling Enzymes Distribution.
Korobkin J; Balabin FA; Yakovenko SA; Simonenko EY; Sveshnikova AN;
Int J Mol Sci. 22(15):8018
PUBMED:34360784
doi:10.3390/ijms22158018
VCell BioModels referenced in publication
user: Juliajessica, biomodel name: SpermCalcium

biomodel-211839191

acowan 2021-09-03T14:11:24+00:00 July 27th, 2021|biomodel|

Name: “SpermCalcium”
Saved: Jul 24, 2021
vcell identifier: biomodel-211839191
Owned by: “Juliajessica
“

download model (.vcml)

2021 Computational Cell Biology Workshop help June 21-23.

acowan 2021-08-17T19:31:49+00:00 June 24th, 2021|News, VCell Posts|

2021-6-24 CCAM’s annual Computational Cell Biology Workshop was again held online June 21-23, 2021. The workshop provided instruction to over 50 individuals from around the world on mathematical modeling techniques using VCell, COPASI and SpringSaLaD software. Fifteen of the participants worked closely with CCAM researchers to develop their own models related to their research projects. Another successful year for the modeling workshop! a combined workshop for VCell, COPASI, and SpringSaLaD modeling software. Thanks to all […]

VCell model of YAP/TAZ

acowan 2021-08-17T19:33:40+00:00 May 8th, 2021|News|

2021-5-08. A new VCell model from the Rangamani lab explores how YAP/TAZ signaling integrates inputs from different biophysical properties of the cell. Find links to the paper and public VCell models on our published models page.

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