VCell model of Axon Initial Segment
2021-4-05. A VCell model was used to assess the role of casein kinase 2 and ankyrin-G on sodium channel recruitment to the axon initial segment. Find links the citation on our published models page.
Bhardwaj et al., 2021
Modeling protein-protein interactions in axon initial segment to understand their potential impact on action potential initiation.
Bhardwaj, P.; Kulasiri, D.; Samarasinghe, S.
Neural Regen Res 2021, 16 (4), 700–706.
PUBMED:33063731
doi:10.4103/1673-5374.295332
VCell 7.4 released
2021-03-23.VCell 7.4 has been released. New in VCell 7.4 is the ability to preview geometries from the VCell database, vastly accelerated multiple trajectory stochastic simulations using the Gibson-Bruck solver, extension of unit display and automatic conversion to rate and assignment rules, support for external access to containerized versions of some VCell solvers with command line execution, as well as numerous additional improvements and bug fixes.
New VCell model of Ras signaling
2021-3-18. A new paper by Kerbai Eroume in the Carlier lab published in PLOS One explores how cell shape affects the signaling mechanisms that determine cell polarization. Find links to the model and citation on our published models page.
Eroume et al., 2021
On the influence of cell shape on dynamic reaction-diffusion polarization patterns.
Eroumé, K.; Vasilevich, A.; Vermeulen, S.; de Boer, J.; Carlier, A.
PLoS One 2021, 16 (3), e0248293.
PUBMED:33735291
doi:10.1371/journal.pone.0248293
VCell BioModels referenced in publication:
user: KerbaicBITE, model name: Kerbai_PLoSone_2021_teardrop_polarization_minimal
user: KerbaicBITE, model name: Kerbai_PLoSone_2021_teardrop_polarization_extended
biomodel-203656156
Name: “Kerbai_PLoSone_2021_teardrop_polarization_extended”
Saved: Mar 25, 2021
vcell identifier: biomodel-203656156
Owned by: “KerbaicBITE”
biomodel-203052143
Name: “Kerbai_PLoSone_2021_teardrop_polarization_minimal”
Saved: Mar 25, 2021
vcell identifier: biomodel-203052143
Owned by: “KerbaicBITE”
Myeong et al., 2020
Phosphatidylinositol 4,5-bisphosphate is regenerated by speeding of the PI 4-kinase pathway during long PLC activation.
Myeong, J.; de la Cruz, L.; Jung, R.; Yeon, J.-H.; Suh, B.-C.; Koh, D.-S.; Hille, B.
J Gen Physiol. 2020. 152 (12): e202012627.
PUBMED:33186442
doi:10.1085/jgp.202012627
VCell BioModels referenced in publication:
user: Myeong, model name: PI cycle Figure 4 & S4
user: Myeong, model name: PI cycle Figure 6, 7 & S9
biomodel-189512756
Name: “PI cycle Figure 6,7 & S9”
Saved: Sep 18, 2020
vcell identifier: biomodel-189512756
Owned by: “Myeong”
biomodel-189513183
Name: “PI cycle Figure 4 & S4”
Saved: Sep 18, 2020
vcell identifier: biomodel-189513183
Owned by: “Myeong”