VCell model of transport in plants
2020-01-30. A VCell model is used in a new paper by Dreyer and Michard to re-examine the concept of high- and low-affinity nutrient uptade systems in plants. Visit our published models page for links to the paper.
VCell 7.2 Released
2019-12-10. VCell 7.2 has been released. See the Release Notes for a full list of the many new features in VCell 7.2 including new functionality to store identifiers and text annotations for model components, a service linking VCell simulation with ImageJ image analysis functions, rate rules and assignment rules in ODE applications, improved SBML import along with several other improvements.
VCell model of cAMP signaling
2019-11-28. VCell was used to create a 2D spatial model of cAMP intracellular signaling in a new publication by Stone and colleagues. Visit our published models page for links to the paper.
20th Annual VCell Short Course
2019-6-18 CCAM hosted a Computational Cell Biology Workshop on June 24-26, 2019, a combined workshop for both VCell and COPASI modeling software. Ten scientists from the US, Netherlands and Germany traveled to work with the VCell and COPASI teams to construct models based on their own research interests. It was exciting to see VCell and COPASI models applied to such interesting cell biology projects. Thanks to all for a very successful course!
New model of GIV/girdin modulation of cyclic AMP signals
2019-06-13. A new Molecular Biology of the Cell publication from the Rangamani lab uses VCell and COPASI to develop a model to examine cross-talk between receptor tyrosine kinases and G proteins that regulate cAMP levels. Visit our published models page for links to the paper and to the VCell Biomodel.
VCell models aid in design of SH2 domain biosensors
2019-06-04. A new publication in Science Signaling from the Haugh and Rao labs describes the use of VCell modeling to assist in designing improved SH2 domain biosensors of EGFR phosphorylation. Visit our published models page for links to the paper and to the VCell Biomodel.
VCell model of RAF1 membrane dynamics published
2019-02-14. A VCell spatial model created to identify mechanisms regulating membrane abundance of the small Gprotein RAF1 at the plasma membrane has been published in Molecular Biology of the Cell. Visit our published models page for links to the paper and to the VCell Biomodel.
VCell model of voltage-sensing phosphatase specificity
2019-02-04. A new publication from the Hille lab uses a VCell model to reveal emergent properties of the behavior of voltage-sensitive phosphatases. Visit our published models page for links to the paper and to the VCell Biomodel.
New VCell analysis of FRAP experiments
2019-01-25. A new publication from Karvinen et al uses VCell models to analyze photobleaching experiments in their characterization of hydrogel properties. Visit our published models page for links to the paper.
VCell 7.1 released
17-11-2018. Announcing the release of VCell 7.1. VCell 7.1 adds the ability to explore existing models in the database and VCell functionality without registration. It has an improved model database info panel with model provenance, annotations, direct links to Pubmed and journal websites for models described in publications. These add to the new features for 2D kinematics to solve simulations with moving boundaries and the ability to use the COMSOL Multiphysics solver already in VCell 7.0.