Mechanopharmaceutical Device (1): Measuring the Cargo Capacity of Macrophages in a Living Organism.
Rzeczycki, P., T. Woldemichael, A. Willmer, M.D. Murashov, J. Baik, R. Keswani, G.S. Yoon, K.A. Stringer, N. Rodriguez-Hornedo, and G.R. Rosania.
Pharmaceutical Research 2018, 36 (1), 12.
doi: 10.1007/s11095-018-2539-6
VCell BioModels referenced in publication:
user: awillmer, model name: Macrophage Cargo Capacity
Name: “An Expandable Mechanopharmaceutical Device (1): Measuring the Cargo Capacity of Macrophages in a Living Organism”
Saved: May 30, 2019
vcell identifier: biomodel-158495696
Owned by: “awillmer”
Name: “Tutorial_MultiApp”
Saved: Aug 14, 2018
vcell identifier: biomodel-233650653
Owned by: “tutorial”
2018-07-10. A new Vcell spatial model of calcium influx, buffering and diffusion in mossy fiber boutons was published by Chamberland and co-authors in PNAS. Visit our published models page for links to the paper.
Action potential counting at giant mossy fiber terminals gates information transfer in the hippocampus.
Chamberland, S., Y. Timofeeva, A. Evstratova, K. Volynski, and K. Toth
Proc Natl Acad Sci U S A. 2018 Jul 10 115: 7434-7439.
PUBMED:29946034 doi:10.1073/pnas.1720659115
2018-6-18 VCell hosted its 19th annual VCell Short Course on June 12-14, 2018. Ten scientists traveled to work with the VCell team to construct Virtual Cell models based on their own research interests. It was exciting to see the breadth of cell biological problems to which VCell models were applied. Thanks to all for a successful time!
Fission yeast myo2: Molecular organization and diffusion in the cytoplasm
Friend, J.E., W.A. Sayyad, R. Arasada, C.D. McCormick, J.E. Heuser, and T.D. Pollard
Cytoskeleton (Hoboken). 2018 Apr 75: 164-173.
PUBMED:29205883 doi:10.1002/cm.21425
VCell BioModels referenced in publication:
user: Wasim, model name: Yeast 3D_FRAP
2018-3-15 Announcing the release of VCell 7.0. VCell 7 includes new 2D kinematics functionality for solving reaction diffusion equations within moving boundaries. To support models of cell motility and morphogenesis, this allows users to specify velocities of points, surfaces and volumes within the geometry. Other features in VCell 7.0 are methods for creating simulated fluorescence for direct comparison to microscopy data, the ability to use COMSOL Multiphysics solver (requires a local COMSOL license) and adaptive meshes for simulating […]
2018-03-13. A paper by Kinglsey et al assesses the effects of complex geometries on FRAP recovery curves. They develop a computational model of the FRAP processes to assess methods of analyzing FRAP experiments. They determined that the Vcell VirtualFRAP tool provides the best accuracy to measure diffusion coefficients. A link to the paper can be found on our published models page.
Src Characterization of cell boundary and confocal effects improves quantitative frap analysis
Kingsley, J.L., J.P. Bibeau, S.I. Mousavi, C. Unsal, Z. Chen, X. Huang, L. Vidali, and E. Tuzel
Biophys J. 2018 Mar 13 114: 1153-1164.
PUBMED:29539401 doi:10.1016/j.bpj.2018.01.013
