Phosphatidylinositol 4,5-bisphosphate is regenerated by speeding of the PI 4-kinase pathway during long PLC activation.
Myeong, J.; de la Cruz, L.; Jung, R.; Yeon, J.-H.; Suh, B.-C.; Koh, D.-S.; Hille, B.
J Gen Physiol. 2020. 152 (12): e202012627.
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Spatially Compartmentalized Phase Regulation of a Ca2+-CAMP-PKA Oscillatory Circuit.
Tenner, B.; Getz, M.; Ross, B.; Ohadi, D.; Bohrer, C. H.; Greenwald, E.; Mehta, S.; Xiao, J.; Rangamani, P.; Zhang, J.
Elife 2020, 9.
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user: mgetz, model name: Minimum Stochastic Model BetaCell
An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling.
Jang, W.; Adams, C.E.; Liu, H.; Zhang, C. Levy; F.O.; Andressen, K.W.; Lambert, N.A.
Proc Natl Acad Sci U S A. 2020. 1172 (48): 30755-30762.
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Breast cancer cells and macrophages in a paracrine-juxtacrine loop.
Onal, S.; Turker-Burhan, M.; Bati-Ayaz, G.; Yanik, H.; D. Pesen-Okvur, D.
Biomaterials. 2021. 267:120412.
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Cell shape regulates subcellular organelle location to control early Ca2+ signal dynamics in vascular smooth muscle cells.
Calizo, R.C.; Bell, M.K.; Ron, A.; Hu, M.; Bhattacharya, S.; Wong, N.J.; Janssen, W.G.M.; Perumal, G.; Pederson, P.; Scarlata, S.; Hone, J.; Azeloglu, E.U.; Rangamani, P.; Iyengar, R.
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Modeling protein-protein interactions in axon initial segment to understand their potential impact on action potential initiation.
Bhardwaj, P.; Kulasiri, D.; Samarasinghe, S.
Neural Regen Res. 2021. 16:700–706.
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Activation of RhoA Allows for Persistent RhoA Signaling.
EZhang, J. Z.; Nguyen, A. H.; Miyamoto, S.; Heller Brown, J.; McCulloch, A. D.; Zhang, J.
PLoS Biol 2020, 18 (9), e3000866.
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Whole-Cell Photobleaching Reveals Time-Dependent Compartmentalization of Soluble Proteins by the Axon Initial Segment.
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Front Cell Neurosci. 2020 14:180.
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Mechanistic Models of PLC/PKC Signaling Implicate Phosphatidic Acid as a Key Amplifier of Chemotactic Gradient Sensing.
Nosbisch, J.L., A. Rahman, M. Krithika, T.C. Elston, J.E. Bear, and J. M. Haugh
PLoS Comput. Biol. 2020. 16(4):e1007708
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user: jnosbis, model name: Nosbisch chemotaxis 2020
Two MYB Proteins in a Self-Organizing Activator-Inhibitor System Produce Spotted Pigmentation Patterns.
Ding, B., E.L. Patterson, S.V. Holalu, J. Li, G.A. Johnson, L.E. Stanley, A.B. Greenlee, F. Peng, H.D. Bradshaw, M.L. Blinov, B.K. Blackman, and Y.-W. Yuan
Current Biology. 30:802-814.e8
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user: colreeze, model name: Monkeyflower_pigmentation_v2
