2020-11-16. A new publication from the Lambert lab investigates the mechanisms that set the dynamic range of agonist-induced signaling using fluorescence imaging coupled with VCell modeling. Visit our published models page for links to the paper and to access the VCell model.
Name: “5HT7_Jan_2020”
Saved: Sep 16, 2020
vcell identifier: biomodel-189512756
Owned by: “wojang”
An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling.
Jang, W.; Adams, C.E.; Liu, H.; Zhang, C. Levy; F.O.; Andressen, K.W.; Lambert, N.A.
Proc Natl Acad Sci U S A. 2020. 1172 (48): 30755-30762.
PUBMED:33199589
doi:10.1073/pnas.2010801117
VCell BioModel referenced in publication:
user: wojang, model name: 5HT7_Jang_2020
2020-9-3. A new VCell model created incollaboration between the McCulloch and Zhang labs helped to demonstrate that a second phase of RhoA activation is required to maintain RhoA-mediated transcription after receptor signalling ends. Find links to the model and paper by Zhang et al. on our published models page.
Breast cancer cells and macrophages in a paracrine-juxtacrine loop.
Onal, S.; Turker-Burhan, M.; Bati-Ayaz, G.; Yanik, H.; D. Pesen-Okvur, D.
Biomaterials. 2021. 267:120412.
PUBMED:33161320
doi:110.1016/j.biomaterials.2020.120412
Cell shape regulates subcellular organelle location to control early Ca2+ signal dynamics in vascular smooth muscle cells.
Calizo, R.C.; Bell, M.K.; Ron, A.; Hu, M.; Bhattacharya, S.; Wong, N.J.; Janssen, W.G.M.; Perumal, G.; Pederson, P.; Scarlata, S.; Hone, J.; Azeloglu, E.U.; Rangamani, P.; Iyengar, R.
Sci Rep. 2020 10:17866.
PUBMED:33082406
doi:10.1038/s41598-020-74700-x
2020-10-20. A new publication from the Rangamani and Iyengar labs using VCell modeling to explore how cell shape affects calcium dynamics in vascular smooth muscle cells. Visit our published models page for links to the paper.
Modeling protein-protein interactions in axon initial segment to understand their potential impact on action potential initiation.
Bhardwaj, P.; Kulasiri, D.; Samarasinghe, S.
Neural Regen Res. 2021. 16:700–706.
PUBMED:33063731
doi:10.4103/1673-5374.295332
Name: “Line1Activity_Full_July10_0202”
Saved: Sep 09, 2020
vcell identifier: biomodel-188880263
Owned by: “seriously”
Activation of RhoA Allows for Persistent RhoA Signaling.
EZhang, J. Z.; Nguyen, A. H.; Miyamoto, S.; Heller Brown, J.; McCulloch, A. D.; Zhang, J.
PLoS Biol 2020, 18 (9), e3000866.
PUBMED:32881857
doi:10.1371/journal.pbio.3000866
VCell BioModels referenced in publication:
user: jzz002, model name: KHistamtine-RhoA- Model_Final3
