About acowan

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So far acowan has created 46 blog entries.

New VCell model of dendritic spines

2017-08-25T17:59:40+00:00 August 30th, 2016|News|

2016-08-30 A recent publication in PNAS describes a VCell model developed as collaboration between the Rangamini group at UC Davis and the Oster lab at UC Berkeley.  The model couples biochemical signaling machinery with actin remodeling events in the dendritic spine; view the details on our Published Models list.

New VCell models of chemotactic networks

2016-11-07T20:00:07+00:00 July 27th, 2016|News, VCell Posts|

2016-07-27   A new publication from Sayak Bhattacharya and Pablo Iglesias at Johns Hopkins University describes the step-by-step construction of dynamical models of chemotactic networks using VCell (Bhattacharya and Iglesias 2016. Methods Mol. Biol. 1407:397, PMID 27271916).  Publically available VCell models associated with the paper can be found on our list of published models here.

New VCell models of cAMP domains

2017-08-25T17:59:40+00:00 July 15th, 2016|News|

2016-07-15 VCell models were used to test possible mechanisms for maintenance of subcellular microdomains of cAMP in cardiomyocytes in a recent publication in PLoS Computational Biology by Yang et al. Find the publication and details of the models on our Published Models listing.

New VCell model of PAR2 desensitization

2017-08-25T17:51:29+00:00 March 15th, 2016|News, VCell Posts|

2016-03-15. A new VCell model  of the mechanisms and kinetics of desensitization of the protease-activated receptor-2 (PAR2), a Gq-PCR, was published by Jung et al. in the Journal of General Physiology.  Visit the Published Models listing to view the model details and link to the publication.

2016-12-06T21:27:29+00:00 February 2nd, 2016|News, NRCAM publication|

2016-02-02 Paul Michalski and Les Loew describe their new Spring SaLaD sofware for spatial, stochastic, particle-based modeling of biochemical systems at the mesoscale. See the publication Michalski and Loew, 2016. SpringSaLaD: A Spatial, Particle-Based Biochemical Simulation Platform with Excluded Volume. Biophysical Journal 110:523-529. PMID 26840718