2026-02-03. Researchers at UConn, UPitt and U Virginia used VCell to model systems-level consequences of low RAF abundance for EGFR-ERK signaling
Biophysical Journal. 2026 Feb 3;125(3):881-900.
https://pubmed.ncbi.nlm.nih.gov/41496453/
Systems-level consequences of low RAF abundance for EGFR-ERK signaling
Lee SH, Myers PJ, Mendrzycki MC, Brown KS, Loew LM, Sorkin A, Lazzara MJ. Biophysical Journal. 2026 Feb 3;125(3):881-900.
PUBMED: 41496453
https://doi.org/10.1016/j.bpj.2025.12.033
VCell BioModels referenced in the publication
user: lazzaralab
biomodel name: Lee 2026 EGFR-RAS-RAF-ERK pathway
2025-12-10. VCell was represented at the American Society of Cell Biology Annual Meeting 2025 in Philaderplphia. On Sunday, December 7th, Michael Blinov together with James Faeder (UPitt) and Margaret Johnson (JHU) presented rule-base modeling methods for Biophysical Modeling of the Cell, including VCell. On Monday, December 8th, Pedro Mendes, Leslie Loew, Ion Moraru, and Michael Blinov presented various modeling techniques using COPASI, VCell and SpringSaLaD during the workshop on Mathematical Modeling for Cell Biology. […]
2025-11-19. Researchers at several Japanase Universities used VCell to model graded regulation of microtubule-binding of Tau by the phosphorylation state of the proline-rich region in living neurons:
Nakata, R., Torii, T., Miyasaka, T. and Misonou, H., 2025. Graded regulation of microtubule-binding of Tau by the phosphorylation state of the proline-rich region in living neurons. Neuroscience Research, p.104987.
https://pubmed.ncbi.nlm.nih.gov/41265727/
Graded regulation of microtubule-binding of Tau by the phosphorylation state of the proline-rich region in living neurons
Nakata, R., Torii, T., Miyasaka, T. and Misonou, H. Neuroscience Research. 2025 Nov 19:104987.
PUBMED:41265727
https://doi.org/10.1016/j.neures.2025.104987
VCell BioModels referenced in the publication
user: nktrnh0108
biomodel name: FRAP_binding_singlestate model
biomodel name: FRAP_binding_Twostate_FSmodel
2025-10-23. Researchers at UConn and University of Cambridge (UK) used VCell to model FRAP in their studies of resistance and germination of spores of Bacillus species lacking members of a spore integral inner membrane protein family and locations of these proteins in spores
Journal of Bacteriology. 2025 Oct 23;207(10):e00217-25.
https://pubmed.ncbi.nlm.nih.gov/40938645/
2025-10-17. Researchers at UConn Health used VCell to aid in detection of dedifferentiated stem cells in the Drosophila testis.
Iscience. 2025 Oct 17;28(10).
https://pubmed.ncbi.nlm.nih.gov/41142995/
Detection of dedifferentiated stem cells in the Drosophila testis
Bener MB, DiPippo SM, Slepchenko BM, Inaba M. Iscience. 2025 Oct 17;28(10).
PUBMED:41142995
https://doi.org/10.1016/j.isci.2025.113564
Role of intercellular interactions on single cell and population level responses: considerations for multicellular bioreporter design.
Douglas Lin & Michael Martin.
Front Mol Biosci, 2025 Oct 13:12:1595363
PUBMED: 41158874
doi.org:10.3389/fmolb.2025.1595363
2025-10-12. Douglas Lin & Michael Martin from University of Louisville created a multicellular simulator implementing the Gillespie algorithm and compatible with Virtual Cell-designed networks to investigate a role of intercellular interactions on single cell and population level responses
Front Mol Biosci, 13:12:1595363. doi: 10.3389/fmolb.2025.1595363. eCollection 2025
https://pubmed.ncbi.nlm.nih.gov/41158874/
