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mblinov

About Michael Blinov

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So far Michael Blinov has created 60 blog entries.

24th Annual Computational Cell Biology (CCB) workshop

2023-07-17T18:51:05+00:00 June 28th, 2023|News|

2023-06-28. The  24th Annual Computational Cell Biology (CCB) workshop took place at the Center for Cell Analysis and Modeling (CCAM) on June 26-28th. 11 participants from all over the US (from Maryland to Illinois) came to Farmington to work on developing their modeling projects using VCell and COPASI software tools, designed and maintained at CCAM. The students were helped by a CCAM team consisting of Michael Blinov, Ann Cowan, Leslie Loew, Pedro Mendes, Ion Moraru, […]

Cowan & Loew, 2023

2023-07-17T23:27:25+00:00 June 23rd, 2023|publication, publication-2023|

Beyond analytic solution: Analysis of FRAP experiments by spatial simulation of the forward problem.
Cowan, A.E. & Loew, L.M.
Biophys J. 2023 Jun 23;S0006-3495(23)00401-0
PUBMED:37353932/
doi: 10.1016/j.bpj.2023.06.013
VCell BioModels referenced in publication
user: les
biomodel name: FRAP_Membrane_Rel
biomodel name: FRAP_Cyt
biomodel name: FRAP_Cyt_Membrane_Binding
biomodel name: FRAP Condensate Droplet

Schaumburger et al., 2023

2023-07-17T23:12:14+00:00 May 4th, 2023|publication, publication-2023|

Dynamic model assuming mutually inhibitory biomarkers of frailty suggests bistability with contrasting mobility phenotypes.
Schaumburger N, Pally J, Moraru II, Kositsawat J, Kuchel GA, Blinov ML.
Frontiers in Network Physiology, 2023 May 4; 3, 1079070
PUBMED:37216041
doi: 10.3389/fnetp.2023.1079070
VCell BioModels referenced in publication
user: aging_project
biomodel name: Aging_Phenotypes

VCell is used in a research on aging

2023-07-17T18:52:57+00:00 May 4th, 2023|News|

2023-05-04. The interdisciplinary team consisting of CCAM modelers Drs. Blinov and Moraru and researchers from the Center on Aging Drs. Kuchel and Kositsawat, together with former undergrad students Schaumburger and Pally published a manuscript theoretically explaining the bistability of clinical outcomes: the likelihood of an individual remaining mobile over time either increases to almost 100% or decreases to almost zero. The VCell software was extensively used for parameter scans and fitting.

Schaumburger, N., Pally, J., Moraru, […]

VCell 7.5 Release

2023-05-01T23:22:29+00:00 May 1st, 2023|News|

2023-05-01. VCell 7.5 has been released. It features parameter estimation from the latest version of COPASI; model exchange via multiple standards, including, SBML, SEDML and OMEX; parameter scans in local client simulations; and hardening of unit handling including automatic unit transformations. Full specs available https://vcell.org/run-vcell-software.

Korza et al., 2023

2023-05-12T20:27:47+00:00 March 12th, 2023|publication, publication-2022|

Expression of the 2Duf protein in wild-type Bacillus subtilis spores stabilizes inner membrane proteins and increases spore resistance to wet heat and hydrogen peroxide.
Korza G, DePratti S, Fairchild D, Wicander J, Kanaan J, Shames H, Nichols FC, Cowan A, Brul S, Setlow P.
Journal of Applied Microbiology. 2023 Mar 1;134(3):lxad040.
PUBMED:36841229
doi:10.1093/jambio/lxad040
VCell BioModels referenced in publication
user: dfairchild
biomodel name: Bacillus Spore Membrane FRAP Analysis

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